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ProbioPure™ features the probiotic, Morinaga BB536, which provides help for occasional constipation, diarrhea, abdominal discomfort, gas and bloating.*

16 reviews


If you’re like millions of other Americans, you experience episodic digestion upsets, such as occasional constipation and diarrhea, abdominal discomfort, gas, and bloating.* But if you thought you just had to put up with digestive troubles, here’s some good news: they are not inevitable! In fact, they are often simply due to a lack of beneficial bacteria (or probiotics).

Morinaga BB536 is a proprietary strain of Bifidobacterium longum developed by Japan’s second-largest dairy company. BB536 is one of the world’s most researched and effective probiotic strains, and the top-selling probiotic ingredient in Japan. Numerous published human clinical trials have shown that BB536:

  • Provides a natural defense against episodic digestive upsets, including occasional constipation and diarrhea, abdominal discomfort, gas, and bloating.*

  • Improves the body’s ratio of beneficial bacteria.*

  • Decreases ammonia and putrefactive products in the digestive tract.*
100% of our Ingredients are Backed by Human Clinical Studies. Click on any ingredient below to view the research abstracts.

Suggested Use: 1 vegicap daily with a meal.

Supplements Facts

Serving Size: 1 vegicap

Servings Per Container: 30

Amount Per Serving

% Daily Value

125 mg †

(Morinaga BB536® proprietary strain,

5 billion CFU)

† Daily value not established.

Other ingredients: tapioca starch, vegetable cellulose, l-leucine, silica, tricalcium phosphate.

BB536® is a registered trademark of Morinaga Milk Industry Co. Ltd.




Morinaga BB536

Bifidobacterium longum is a type of beneficial bacteria, or probiotic, that promotes healthy digestion.* BB536 is a proprietary strain of B. longum and one of the most well-researched and effective probiotics available. Many human clinical studies have shown BB536 supports a healthy microbial balance in the gut and relieves symptoms of occasional constipation, diarrhea, and indigestion (particularly flatulence), while decreasing ammonia and putrefactive products in the GI tract.*


Q: Why should Bifilon be taken with meals?

A: If taken with meals, the food can protect BB536 when it goes through the stomach acid.  So while it takes longer to reach the intestines than would be the case if it was taken before a meal, we feel that protecting the BB536 is more important. If you would still rather take BB536 on an empty stomach without food, then we would recommend that it be taken with milk, since the milk could also protect BB536 by adjusting the pH before entering the stomach.    

Customer Reviews
4.8 Based on 16 Reviews
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Anica R.
United States United States

Great Product! Works Well

United States United States

Great probiotic!!!

Probio pure probiotic has been my most favorite probiotic and I have tried several! It doesn’t give me any digestive upset like previous brands have given me. I have been very pleased with the price and quality of this probiotic!

Fernando Alvarez Sr.
United States United States

Recommend ProbioPure

I’m on my second bottle and I’m going to continue to buy, I used to buy another brand but I feel Quality of Life Supplements are better tested and quality control.

Elias P.
United States United States

Feel much better!

I used the product and it really made me feel much better.

Cynthia R.
United States

My Miracle!

I have endured intestinal issues my entire life and have tried many brands of probiotics! I take one ProbioPure capsule in the morning as instructed and it works within 30 minutes! I highly recommend this amazing probiotic for anyone looking for a highly-rated probiotic!

Debbie B.
United States

Help for Histamine

ProbioPure seems to be helping with my histamine intolerance. My reactions are milder and not having as many as I was. I am glad I gave it a try!

Don G.
United States

Unique and reasonably priced

It's a good quality formula. A welcome addition to my other supplements.

A Quality of Life Labs Customer
Stanley S.
United States

A useful product

The product is known to be helpful. I've been using it for some time.

Tyler D.
United States

Working Well So Far...

I'll be buying more of this product.


I like the single strain probiotics — it is easier to ...

So far this is making a difference for me. I like the single strain probiotics — it is easier to assess impact of the product.


Second time purchasing

Very pleased with purchase and service. Product was and is highly recommended


The Best

Best probiotic I've ever used. The only one that has improved my situation.


After only one week of taking one capsule morning and ...

After only one week of taking one capsule morning and night - and making homemade yogurt specifically cultured with these probiotics, consuming one cup twice a day - constipation is significantly less. These really do seem to work. There are studies online which show what this particular strain of probiotics can do, and in our case, they proved true. It has definitely helped.


Beware, no live culture in this "probiotic"

I always test every probiotic I receive by inoculating milk in a yogurt maker. This "probiotic" did nothing to the milk. Tried twice just to make sure, using 2 caps each time. Not sure if I got a bad batch or this is not a probiotic at all.

B. Good

Wonderful. It just works!!

I know finding a probiotic that works can be frustrating. And what works for one may not work for another. So I'm somewhat reluctant to recommend one over another. Suffice to say this particular brand, and this strain in particular has been a blessing. It just works! I love it and will definitely reorder. I also like that it's a single strain, as often with multi strain products some may be helpful but others not so much.

Emily S. Bradburn

Five Stars

Best on the market!! Believe me Iv'e tried them all this product is second to none!!

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Disclaimer: Reviews and ratings are provided for informational purposes only and solely reflect the views and opinions expressed by the individual contributors and not those of Quality of Life. Your results and experience with the product may differ.