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AHCC® is an effective, well-absorbed and proprietary mushroom extract backed by over 30 human clinical studies.

71 reviews

The immune system is complex.

Like, really complex...

If it’s under active your defenses are low, if it’s overactive then it can attack the body by mistake. Talk about sensitive!

Let’s make it a little less complicated shall we?

Introducing Quality of Life’s AHCC supplements. All-natural, safe, immunomodulating supplements that work to improve overall immune system performance, increase the activity of certain white blood cells and fill your body with energy!


A cultured extract of hybridized medicinal mushroom mycelia (roots), AHCC® is one of the world's most researched specialty immune supplements, supported by over 30 human clinical studies.

AHCC has been shown to:

  • Maintain optimal NK cell activity.*
  • Increase number and activity of dendritic cells.*
  • Promote T-cell and macrophage activity.*
  • Enhance cytokine production.*

Providing 67% greater potency, each 300 mg softgel of AHCC-Rx is equivalent to one 500 mg capsule of AHCC. The new, smaller softgels are easy to swallow and enable a divided AM/PM dose.

100% of our Ingredients are Backed by Human Clinical Studies. Click on any ingredient below to view the research abstracts.

Suggested Use: 2 softgels (up to 3 times) daily before meal.

Supplements Facts

Serving Size: 2 softgels 

Serving Per Container: 30

Amount Per Serving

% Daily Value

600 mg

Mycelia extract of hybridized basidiomycetes (Lentinula edodes) mushrooms (with acetylated alpha-glucans), dextrin (tapioca), alpha-cyclodextrin (vegetable)

Daily value not established.

Other ingredients: soybean oil, soy lecithin, beeswax (yellow), fumed silica, food starch, carrageenan, glycerin, sorbitol, purified water, caramel powder.





AHCC® is a patented, low-molecular weight medicinal mushroom extract developed from the mycelia (or underground portion) of a particular subspecies of Lentinula edodes. Supported by more than 30 human clinical studies, AHCC prompts an early activation of the immune system.* It works by enhancing the production of cytokines (immune-signaling molecules) and increasing the activity of certain white blood cells, including NK cells, DC cells, T-cells, and macrophages.*


Q: What is the difference between the AHCC used in the AHCC Rx formula and the AHCC used in the Kinoko Gold and Platinum products?

A: The AHCC used in AHCC Rx (called AHCC FD) has a higher potency than the regular AHCC used in our other AHCC products. Each 300 mg softgel of AHCC Rx is equivalent to one 500 mg capsule of regular AHCC.

Q: If I am allergic to mushrooms can I take AHCC?

A: Allergies to mushrooms are most often associated with exposure to mushroom spores. These spores originate in the top of the mushroom, called the fruiting body. However, AHCC is derived from the mycelia, or the root of the mushroom, which does not contain spores. In addition, as part of the manufacturing process, the raw material is subjected to a fermentation process that breaks down the high molecular weight molecules that are very tough to digest, into low molecular weight compounds. This process further lowers any allergenic potential. Many people who believe they are allergic to mushrooms take AHCC successfully. However, if you are concerned, please check with a healthcare professional that specializes in natural products or begin taking AHCC very slowly. This can be done by starting with a quarter of a capsule on the tip of your tongue and if you don't experience itching in your mouth or other signs of allergy, work your way up to 2 to 6 capsules per day over a period of several days.

Q: Does AHCC lose its effectiveness over time? 

A: No AHCC does not lose its effectiveness overtime. As shown in an AHCC placebo controlled scientific trial, patients who used AHCC regularly over a ten year period had consistent and significant improvement as compared to the placebo group, therefore showing no signs of the ingredient losing effectiveness.*

Q: Can AHCC be taken with other medications?

A: Two studies conducted at the highly prestigious MD Anderson Cancer Center and published in the Journal of Integrative Oncology explored AHCC’s interaction with other medications. These studies determined that AHCC is metabolized via a pathway called “P450 2D6,” meaning that AHCC has the potential to increase or decrease the absorption of a drug that uses the same pathway. There are few drugs that use the P450 2D6 pathway. In case of cancer treatment, the only mainline chemotherapies that use this pathway are Doxorubicin and Tamoxifen while other chemotherapeutic drugs use different pathways from the one used by AHCC.

Therefore if you are taking another medication and are concerned about possible interactions, we recommend you ask a medical professional if the drug you are taking is metabolized through the cytochrome P450 2D6 class of enzymes. Most likely the answer will be “no” which means that AHCC is highly unlikely to interact with the drug you are taking.


For more information about AHCC, please visit www.ahccresearch.com

Customer Reviews
4.6 Based on 71 Reviews
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Filter Reviews:
United States United States

Great Product for immune support, fast shipping, highly recommend.

United States United States
I love this stuff!

AHCC has really helped me stay healthy and strong. I love it and feels so good when I’m taking it every say.

Quality of Life Labs AHCC® Rx Review
Jessica B.
United States United States
So far, so good!

So far, so good!

United States United States
Great Product

Always on time with my delivery every month with auto ship. Love these products.

Quality of Life Labs AHCC® Rx Review
Kevin W.
United States United States

Service has been god

United States United States
Love the product.

Great product great company, always arrives on time really feel the immune boosting properties.

Igor R.
United States United States

Excellent quality! I recommend

United States United States

I have been a long time user of the AHCC Gold, and I’m disappointed that it’s been out of stock for so long. However, I’m very grateful that AHCC Rx was available! I like the gel caps and that you get the same benefits with a smaller dose! 

United States United States

Love this product.

Wilbert R.
United States United States
Good Product

I am enrolled in a month to month subscription. But once every other month would be a nice feature. This would save me shipping cost and help out in that way.

United States United States
Ahcc rx

This supplement is full of energy!

United States United States
Very good product

Just taking it for 30 days but I feel very comfortable with the taste and how I feel.

United States United States
Good stuff!

After researching lots about AHCC I have found it an imperative supplement to add to your life. Truly amazing product.

United States United States

Quality product.

Sonia S.
United States United States
Excellent immune builder

I have been taking AHCC this year and it has kept my immune system strong! It is a must have supplement for me!

Justin H.
United States United States
Do they work?

So I've been buying and taking QoL products for about 11 months now. 13 bottles (60 count) of AHCC as well as 3 bottles (30 count) AHCC Rx. Not sure if any change or beneficialness that I can contribute these products to as I was not sick prior to taking AHCC but I hope to think they are!

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Disclaimer: Reviews and ratings are provided for informational purposes only and solely reflect the views and opinions expressed by the individual contributors and not those of Quality of Life. Your results and experience with the product may differ.