Highlights
- Clinically researched doses of all ingredients
- 5-HTP, the natural precursor of serotonin
- Relora®, a standardized blend of magnolia and Phellodendron bark extracts
- L-theanine, a calming amino acid
- Vegan, gluten-free, GMO-free
Benefits
- Helps balance serotonin and cortisol levels*
- Promotes a positive outlook*
- Reduces stress and stress-related eating*
- Supports healthy sleep*
- Bolsters immunity*
Why Serotonin (PureBalance™)
Serotonin is a brain chemical that regulates mood, appetite, sleep, and immunity. The body normally contains 10-12 mg, but this tiny amount has an outsize effect on your physical and mental well-being. Even a small imbalance in serotonin levels can cause low mood, stronger-than-normal appetite, cravings for carbohydrates, poor-quality sleep, and weakened immunity.
You can’t take serotonin supplements or drugs orally because it doesn’t cross the blood-brain barrier. However, there is a way to naturally help balance your serotonin levels. Introducing PureBalance™ Serotonin.
Our highly-rated formula starts with 5-HTP — an amino acid your body uses to make serotonin. Unlike oral serotonin, oral 5-HTP does cross the blood-brain barrier, providing your brain with the raw material it needs to increase serotonin production. Clinical human research has confirmed that taking 5-HTP effectively raises serotonin levels.*
In addition to 5-HTP, PureBalance™ Serotonin also includes ingredients that reinforce the actions of serotonin for mood support, stress management, weight control, and quality sleep.*
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100%
Dairy-Free -
100%
Gluten-Free -
100%
GMO-Free -
Magnesium
Stearate Free -
100%
Vegetarian
Loved by 50,000+ Customers
See all our reviews here
Just what I needed
This helped me a great deal. I feel balanced, calm and many times even cheerful all throughout.
Diana B.
Feel Great
Just started taking them but I feel great. I'm looking forward to this new journey.
Charitha H.
Working great
It’s working nicely. My emotions have evened out and I’m not as agitated
Joel T.
Serotonin
After taking them for about a week I noticed the difference in my whole mindset. I was sleeping better and less anxious.
Pat C.
So far so good!
I've been using this for about 6 months now and I have noticed an over all balance of my mood! I have been consciously trying to move my body and enjoy outside activities. Sunshine & exercise helps boost the serotonin even more. I'm more stable and happy and not quick to get flustered. I have added Serenelle about 3 weeks ago and they pair perfectly!
Mary B.
Outstanding!
Pure Balance Serotonin is the best. Wish I had had it a long time ago.
William M.
Just what I needed
This helped me a great deal. I feel balanced, calm and many times even cheerful all throughout.
Feel Great
Just started taking them but I feel great. I'm looking forward to this new journey.
Working great
It’s working nicely. My emotions have evened out and I’m not as agitated
Serotonin
After taking them for about a week I noticed the difference in my whole mindset. I was sleeping better and less anxious.
So far so good!
I've been using this for about 6 months now and I have noticed an over all balance of my mood! I have been consciously trying to move my body and enjoy outside activities. Sunshine & exercise helps boost the serotonin even more. I'm more stable and happy and not quick to get flustered. I have added Serenelle about 3 weeks ago and they pair perfectly!
Outstanding!
Pure Balance Serotonin is the best. Wish I had had it a long time ago.
Learn more about
our ingredients

5-HTP is one of the amino acids the body uses to make serotonin, a neurotransmitter that regulates mood, appetite, sleep, and immunity. When levels of 5-HTP rise, so do levels of serotonin. 5-HTP is a better choice for raising serotonin levels than L-tryptophan because it is converted into serotonin more efficiently, and it crosses the blood-brain barrier more effectively.
Click here to view the research abstracts.

Native to Siberia and other cold regions, Rhodiola Rosea is an adaptogen, a herb that helps the body adapt to stress.* Rhodiola increases levels of chemicals the brain needs for positive mood, calmness, and motivation, such as serotonin, norepinephrine, and dopamine.* The Rhodiola in PureBalance™ Serotonin is standardized to 5% rosavins, the active constituent.
Click here to view the research abstracts.

Vitamin D is often called the “sunshine vitamin” because the body can synthesize it when sunlight exposure is adequate. However, researchers have discovered that vitamin D insufficiency is surprisingly common, affecting as much as 70 percent of the population. Vitamin D boosts brain chemicals needed for a positive mood and modulates immune function.* The D3 form of vitamin D is better absorbed than the D2 form.
Click here to view the research abstracts.

Relora is a proprietary blend of two standardized herbal extracts: magnolia and Phellodendron bark. It may reduce occasional stress and stress-related overeating by lowering levels of cortisol — a hormone that increases both appetite and fat formation.* A double-blind, placebo-controlled human clinical trial found Relora® helped women prone to stress eating control their weight.* *
Click here to view the research abstracts.

L-theanine is an amino acid found in green and black tea. It has been shown in human clinical research to create a state of relaxed alertness by increasing the production of alpha brain waves.* One of the best things about L-theanine is that it works fast, reducing stress within one hour.*
Click here to view the research abstracts.
100% of our ingredients are backed by human clinical studies.
Click on any of the ingredients below to view the research abstracts.
Suggested Use: 1 capsule three times daily before meals.
Serving Size: 1 capsule | Servings Per Container: 90 |
Amount Per Serving | % Daily Value |
---|---|
Vitamin D3 (as cholecalciferol) | 267 IU 67% |
5-HTP (L-5 hydroxytryptophan) (fromGriffoniasimplicifolia) (seed) |
33 mg † |
L-theanine | 67 mg † |
Relora® proprietary blend Magnolia standardized bark extract Phellodendron standardized bark extract |
250 mg † |
Rhodiola extract (root) (Standardized for 5% rosavins [6 mg]) |
120 mg † |
*Percent values are based on a 2,000 calorie diet † Daily value not established. |
Other ingredients: vegetable cellulose, leucine, pregelatinized food starch, corn starch, silica, olive oil, tapioca dextrin.

Dosage Chart
Ingredients | Daily Dose Used in Human Studies | Daily Dose Used in Serotonin (PureBalance™) |
---|---|---|
5-HTP | 50 - 150 mg | 100 mg |
L-theanine | 50 - 200 mg | 200 mg |
Relora® | 750 mg | 750 mg |
Rhodiola rosea | 340 - 680 mg | 360 mg |
Vitamin D3 | 400 - 800 IU | 800 IU |
Serving size: 1 capsule ● Daily dose: 3 capsules
Directions for use
Serving Size | Daily Dose | When to take | How to take |
---|---|---|---|
1 Vegicap | 3 Vegicaps | 3 Vegicaps a day | Between meals |
It's Not You — It’s Your Brain Chemistry
If you have trouble maintaining a positive mood, confidently handling stress, getting quality sleep, or losing weight — take heart. There is significant evidence to suggest that people who suffer from even a slight imbalance in bodily serotonin levels may experience low mood, difficulty coping with stress, sleeplessness, stronger-than-normal appetite, and increased food cravings.
When you buy Serotonin, you get the raw materials your body needs to make serotonin, along with additional ingredients that help with mood, stress, sleep, and appetite. Try and see why PureBalance™ Serotonin is one of our most highly-rated products!
Trust, Efficacy, and Our Promise
We are the only brand in the supplement industry that can guarantee that every single ingredient in every one of our products is backed by human studies and delivered in doses consistent with clinical research
No exceptions, no compromises.

Satisfaction
Guarantee
You can return items purchased directly from Quality of Life Labs for any reason within 30 days of purchase. See our Returns page for full details.

Protectively
Packaged in the USA
We package almost all of our products in glass bottles with metal lids for one simple reason: Glass and metal do the best job of protecting our supplements from light, oxygen, and moisture — all of which can degrade vitamins, minerals, botanicals, and other nutraceuticals and lessen their potency and freshness.

Dosages
Matter
When you choose Quality of Life, you can trust your supplements to work, because 100 percent of the ingredients in every product we manufacture are provided in dosages that match the clinical research.
Frequently Asked Questions
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Can you take Serotonin while taking antidepressants?
According to a study conducted by the University of Maryland, there are dangers in consuming both 5HTP and SSRIs (Selective serotonin reuptake inhibitors) together. This can cause a dangerous serotonin syndrome that can lead to a coma. In general, you should be aware of your intake of medications that affect your serotonin levels if you are considering taking Serotonin. Please consult with your doctor if you have any concerns.
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What is the difference between all your mood products?
Our two mood support products are Serenelle and Serotonin. These products offer the following benefits:
Serenelle - Reduces stress without drowsiness by balancing your body's hormones and improving mental alertness.*
PureBalance™ Serotonin - May increase levels of serotonin within the body. Increased levels of serotonin decrease food cravings and appetite, increase overall mood and decrease occasional stress.*
Customer Reviews
Quality of Life's Satisfaction Guarantee
You can only return items purchased directly from Quality of Life Labs for any reason within 30 days of purchase. You will receive a full refund for unopened items in the original form of payment and merchandise credit for opened items.