Serotonin (PureBalance™)

PureBalance Serotonin provides the raw material for your body to make serotonin,* with additional ingredients that help with mood, sleep and appetite.


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If you have difficulty losing weight, there could be a simple physiological reason: low levels of serotonin. That’s because a proper balance of serotonin is important for positive mood states, good quality sleep, and a normal appetite. PureBalance™ Serotonin includes 5-HTP, the raw material the body uses to make serotonin.* The actions of serotonin are reinforced with ingredients for:

  • Weight control: Relora® may reduce stress and stress-related eating.*

  • Stress management: Rhodiola rosea helps the body adapt to stress, while L-theanine increases the generation of relaxing alpha brain waves.*

  • Mood support: Insufficient vitamin D may negatively affect mood, while Rhodiola rosea has been used for centuries to promote a positive outlook.*

  • Sleep support: L-theanine encourages the transition from the beta brain waves of mental arousal to the alpha brain waves of relaxation.* Combined with a healthy diet and plenty of exercise, PureBalance Serotonin gives you the support you need to cheer up and slim down.*
100% of our Ingredients are Backed by Human Clinical Studies. Click on any ingredient below to view the research abstracts.

Suggested Use: 1 capsule three times daily before meals.

Supplements Facts

Serving Size: 1 capsules

Servings Per Container: 90

Amount Per Serving

% Daily Value

Vitamin D3 (as cholecalciferol)

267 IU 67%

5-HTP (L-5 hydroxytryptophan)

33 mg †

(fromGriffoniasimplicifolia) (seed)


67 mg †

Relora® proprietary blend

250 mg †

Magnolia standardized bark extract

Phellodendron standardized bark extract

Rhodiola extract (root)

120 mg †

(Standardized for 5% rosavins [6 mg])

*Percent values are based on a 2,000 calorie diet
† Daily value not established.

Other ingredients: vegetable cellulose, leucine, maltodextrin, pregelatinized food starch, corn starch, silica, sucrose.




Vitamin D3 (cholecalciferol)

Vitamin D is often called the “sunshine vitamin” because the body can synthesize it when sunlight exposure is adequate. However, researchers have discovered that vitamin D insufficiency is surprisingly common, affecting as much as 70 percent of the population. Vitamin D is a great multi-tasker: it strengthens bone by aiding calcium absorption, modulates immune function, protects prostate cells, and boosts brain chemicals needed for positive mood.* Vitamin D3 is better absorbed than vitamin D2.*

5-HTP(L-5 Hydroxy- tryptophan)

5-HTP is naturally occurring amino acid and the raw material the body uses to make serotonin — a brain chemical necessary for positive mood, healthy sleep, and appetite. Research has shown that when levels of 5-HTP rise, so do levels of serotonin. Several double-blind, placebo-controlled human trials have found 5-HTP can help support a positive mood, reduce appetite, and enhance weight loss.*

Rhodiola root extract

Rhodiola rosea (also called golden root) is a plant that grows in cold regions across the world. Rhodiola is an adaptogen, meaning it helps the body adapt to various stressors. It supports a positive mood by increasing levels of serotonin and other neurotransmitters such as norepinephrine and dopamine, helping them cross the blood-brain barrier, and decreasing MAO (monoamine oxidase), which degrades these chemicals.*


Relora is a proprietary blend of standardized extracts of magnolia and phellodendron bark. It contains the calming compounds berberine and honokiol and may alleviate symptoms of occasional stress and stress-related overeating by reducing levels of the stress hormone coritsol.* Cortisol causes weight gain by increasing both appetite and fat formation, so a reduction in this hormone helps support weight loss efforts in two ways.*


L-theanine is an amino acid found in tea leaves, particularly green tea. It has been clinically shown to prevent over-stimulation and produce a state of relaxed alertness by producing calming alpha brain waves.* L-theanine works by raising levels of several inhibitory neurotransmitters, including serotonin and GABA, and by preventing L-glutamic acid, an excitatory neurotransmitter, from binding to receptors.*

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Q: Can you take Serotonin while taking antidepressants?

A:  According to a study conducted by the University of Maryland, there are dangers in consuming both 5HTP and SSRI's (Selective serotonin reuptake inhibitors) together. This can cause a dangerous serotonin syndrome that can lead to a coma. In general, you should be aware of your intake of medications that affect your serotonin levels if you are considering taking Serotonin. Please consult with your doctor if you have any concerns.

Q: What is the difference between all your mood products?

A: Our three mood support products are Positelle, Sernelle and Serotonin. All of which offer separate benefits:

Positelle - Supports a positive mood, calmness, and a restful sleep.*

Serenelle - Reduces stress without the drowsiness by balancing the hormones in your body and also improving metal alertness.*

PureBalance Serotonin - May increase levels of serotonin within body. Increased levels of serotonin decrease food cravings and appetite, increase overall mood, and decrease occasional stress.*

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Ramon V.
United States


Excelent Thank you


A lot of different in my mind and mood



Wonderful anxiety blockers

I didn't realize how wonderful these supplements make you feel. My mother in law recommended a serotonin supplement to help with anxiety and these help wonders.


Five Stars

Works really well for my mood.

Christina E. Curry

Five Stars

Truly noticed a difference in mood very quickly.